Investigating what treatment leaves unresolved
Biomedical Research is the home for NEUVIOR’s biological and therapeutic research, with glioblastoma as the initial focus through 2030.
We investigate disease mechanisms whose better understanding could support a new therapeutic approach. Our work connects biological questions with the practical requirements of developing an intervention: the model in which it is tested, the cells it affects, the exposure it needs, and the functions a treatment must preserve.
Our initial focus
The Glioblastoma Recurrence Programme examines malignant cells that survive treatment and the conditions that allow regrowth. We want to understand which survivors contribute to recurrence and whether their contribution offers a useful opportunity for intervention.
This brings cell identity, treatment history, and functional response into the same research question. A change in a marker can be informative. A convincing therapeutic rationale also needs to explain what happens to regrowth and to the surrounding neural system.
The human purpose of the work
A future treatment would become part of a person’s life. Function, communication, independence, and treatment burden matter to the question of what a useful benefit would look like.
We are developing patient and caregiver involvement alongside the scientific programme so that these priorities can inform the choices made early in research.
A programme open to expertise
Current work centres on scientific design, model and candidate assessment, specialist discussions, and involvement planning. We welcome researchers whose methods can help distinguish a plausible biological idea from an intervention worth developing.