{ "schemaVersion": "1.0", "id": "neuvior-public-data-foundation", "checkedAt": "2026-10-13T23:32:26.319821+00:00", "publicName": "NEUVIOR Data Analysis", "sourceCount": 14, "serviceStatus": "Local prototype; no scheduled ingestion, alerting service or NEUVIOR.API launch", "analysisClasses": [ { "id": "public_analysis", "label": "Public analysis", "meaning": "Reproducible calculations from a named public source, with dates, scope and methods." }, { "id": "hypothesis", "label": "Research hypothesis", "meaning": "An interpretation or proposed question requiring independent testing." }, { "id": "study", "label": "Evidence study", "meaning": "A separately designed investigation; planned, running and completed status must be evidenced." } ], "sources": [ { "id": "pca", "title": "Prescription Cost Analysis", "publisher": "NHS Business Services Authority", "area": "medicines", "sourceCadence": "Annual", "integrationStatus": "analysed", "scope": "England community dispensing; financial-year totals and product classifications", "question": "How does activity differ from ingredient-cost concentration?", "url": "https://www.nhsbsa.nhs.uk/statistical-collections/prescription-cost-analysis-england/prescription-cost-analysis-england-202526", "licence": { "name": "Open Government Licence v3.0", "url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/", "status": "verified" }, "latestObservedPeriod": "2025/26", "currentResourceUrl": "https://nhsbsa-opendata.s3.eu-west-2.amazonaws.com/pca/pca_summary_tables_2025_26_v001.xlsx", "retrieval": { "url": "https://nhsbsa-opendata.s3.eu-west-2.amazonaws.com/pca/pca_summary_tables_2025_26_v001.xlsx", "retrievedAt": null, "verifiedAt": "2026-10-13T12:21:27Z", "timeBasis": "Existing source-manifest verification; exact original download completion not retained", "sha256": "56d842e23c458a4cedaf1dec9de0200b5f1b26a3bccb795dc0f0069d7ccde6fe", "bytes": 16227353 }, "notes": [ "21 chapter rows and 1,944 medicinal chemical-substance rows analysed. All 15 medicinal chapters reconcile to the original workbook.", "NIC is not final NHS expenditure or pharmacy margin; items are not patients.", "The original transfer completion time was not separately retained. The recorded local verification date and file hash establish this snapshot\u2019s custody." ], "citation": "NHS Business Services Authority (2026) Prescription Cost Analysis. Available at: https://www.nhsbsa.nhs.uk/statistical-collections/prescription-cost-analysis-england/prescription-cost-analysis-england-202526 (Accessed: 13 October 2026)." }, { "id": "epd", "title": "English Prescribing Dataset with SNOMED Code", "publisher": "NHS Business Services Authority", "area": "medicines", "sourceCadence": "Monthly", "integrationStatus": "metadata_retrieved", "scope": "Prescriptions issued in England, with the publisher\u2019s stated community-dispensing coverage", "question": "Which product and organisational patterns merit a closer investigation?", "url": "https://opendata.nhsbsa.net/dataset/english-prescribing-dataset-epd-with-snomed-code", "licence": { "name": "Open Government Licence v3.0", "url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/", "status": "verified" }, "latestObservedPeriod": "July 2026", "currentResourceUrl": "https://opendata.nhsbsa.net/dataset/906115a6-4155-44be-8b81-f8e83cebfb84/resource/31ae0413-fa45-4fe4-9a76-e884659b4936/download/epd_snomed_202607.csv", "retrieval": { "url": "https://opendata.nhsbsa.net/api/3/action/package_show?id=english-prescribing-dataset-epd-with-snomed-code", "retrievedAt": "2026-10-13T22:53:19.278813+00:00", "sha256": "92a7e98721d6913a8bd6cb8eb8ded1d7f2c2940ec4f491942a10cd44063c8756", "bytes": 705159, "verifiedAt": null, "timeBasis": "Recorded download completion" }, "notes": [ "Current replacement for the retired English Prescribing Dataset. Metadata and resource catalogue retrieved; monthly prescribing files have not been ingested.", "Latest observed monthly resource is 7,788,728,408 bytes; bulk acquisition needs a storage and validation plan.", "A limit-zero metadata request verified the July 2026 datastore schema, including SNOMED_CODE as STRING. No prescribing rows were fetched.", "NHSBSA corrected SNOMED_CODE to string, including a reintroduced April 2026 issue. Preserve identifier strings and re-run affected outputs.", "EPD and PCA differ in prescribing versus dispensing coverage; national totals cannot be joined without checking definitions." ], "citation": "NHS Business Services Authority (n.d.) English Prescribing Dataset with SNOMED Code. Available at: https://opendata.nhsbsa.net/dataset/english-prescribing-dataset-epd-with-snomed-code (Accessed: 13 October 2026)." }, { "id": "mhra", "title": "Medicines and device safety communications", "publisher": "Medicines and Healthcare products Regulatory Agency", "area": "medicines", "sourceCadence": "Event-driven; monthly roundup also published", "integrationStatus": "snapshot_retrieved", "scope": "Official recalls, device communications, field safety notices and patient safety alerts", "question": "Which official communication should a responsible team read next?", "url": "https://www.gov.uk/drug-device-alerts", "licence": { "name": "Open Government Licence v3.0", "url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/", "status": "verified" }, "latestObservedPeriod": "Feed updated 13 October 2026", "currentResourceUrl": "https://www.gov.uk/drug-device-alerts.atom", "retrieval": { "url": "https://www.gov.uk/drug-device-alerts.atom", "retrievedAt": "2026-10-13T22:51:20.257208+00:00", "sha256": "1ffa6e8432320fa23b9ac94d99ba17fe75bb5da6f69da62c8d008d18959c4615", "bytes": 34672, "verifiedAt": null, "timeBasis": "Recorded download completion" }, "notes": [ "Bounded feed snapshot: 50 entries, not the complete historical inventory. Source updated timestamps are not necessarily first issue dates.", "Snapshot indexing is not a recall-compliance service, product-level match or clinical recommendation. Always read the current full official communication." ], "citation": "Medicines and Healthcare products Regulatory Agency (n.d.) Medicines and device safety communications. Available at: https://www.gov.uk/drug-device-alerts (Accessed: 13 October 2026)." }, { "id": "dmd", "title": "Dictionary of medicines and devices", "publisher": "NHS Business Services Authority and NHS England", "area": "terminology", "sourceCadence": "Weekly", "integrationStatus": "access_review", "scope": "UK medicinal products and devices; structured product and pack identities", "question": "Can the same product identity be followed consistently across sources?", "url": "https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/nhs-dictionary-medicines-and-devices-dmd", "licence": { "name": "Open Government Licence v3.0", "url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/", "status": "verified" }, "latestObservedPeriod": "Guidance checked; release not acquired", "currentResourceUrl": null, "retrieval": { "url": "https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/nhs-dictionary-medicines-and-devices-dmd", "retrievedAt": "2026-10-13T22:51:20.666742+00:00", "sha256": "8377c3d340458095782d4538dc244cd8a37acc39f57175650fc5135dd325a93d", "bytes": 69673, "verifiedAt": null, "timeBasis": "Recorded download completion" }, "notes": [ "Guidance retrieved. Full weekly XML release not downloaded. TRUD registration and applicable download terms must be completed through the normal route.", "dm+d content has OGL coverage in the NHS terminology licence table; that does not make all SNOMED CT content openly redistributable." ], "citation": "NHS Business Services Authority and NHS England (n.d.) Dictionary of medicines and devices. Available at: https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/nhs-dictionary-medicines-and-devices-dmd (Accessed: 13 October 2026)." }, { "id": "snomed", "title": "SNOMED CT UK edition and Drug Extension", "publisher": "NHS England and SNOMED International", "area": "terminology", "sourceCadence": "Edition-specific; UK Drug Extension every four weeks", "integrationStatus": "licence_gate", "scope": "Clinical terminology, relationships and UK medicinal terminology", "question": "What does a concept mean in the correct edition and release?", "url": "https://digital.nhs.uk/services/terminology-and-classifications/snomed-ct", "licence": { "name": "SNOMED CT UK National Release Affiliate Licence", "url": "https://digital.nhs.uk/services/terminology-server/content-licences-agreement", "status": "registration_and_licence_required" }, "latestObservedPeriod": "No terminology release acquired", "currentResourceUrl": null, "retrieval": null, "notes": [ "No full SNOMED terminology download, licence acceptance or registration performed.", "Public SNOMED identifiers within an OGL prescribing table do not establish permission to redistribute the complete terminology or deploy it internationally." ], "citation": "NHS England and SNOMED International (n.d.) SNOMED CT UK edition and Drug Extension. Available at: https://digital.nhs.uk/services/terminology-and-classifications/snomed-ct (Accessed: 13 October 2026)." }, { "id": "bnf-mapping", "title": "BNF and SNOMED mapping", "publisher": "NHS Business Services Authority", "area": "terminology", "sourceCadence": "Monthly", "integrationStatus": "catalogued", "scope": "VMP, AMP, VMPP and AMPP records with BNF mappings", "question": "Do codes join to the correct product level and reporting month?", "url": "https://www.nhsbsa.nhs.uk/prescription-data/understanding-our-data/bnf-snomed-mapping", "licence": { "name": "File-specific reuse and terminology terms to verify", "url": "https://www.nhsbsa.nhs.uk/prescription-data/understanding-our-data/bnf-snomed-mapping", "status": "verify_before_ingestion" }, "latestObservedPeriod": "July 2026 data, published September 2026", "currentResourceUrl": null, "retrieval": null, "notes": [ "Publisher plans a phased migration to the Open Data Portal from October 2026; the connector must tolerate a changed publication location.", "Mapping file not downloaded; no joins or match-rate claims made." ], "citation": "NHS Business Services Authority (n.d.) BNF and SNOMED mapping. Available at: https://www.nhsbsa.nhs.uk/prescription-data/understanding-our-data/bnf-snomed-mapping (Accessed: 13 October 2026)." }, { "id": "dms", "title": "Discharge Medicines Service claims", "publisher": "NHS Business Services Authority", "area": "medicines", "sourceCadence": "Monthly", "integrationStatus": "catalogued", "scope": "Claim-submission month, complete and incomplete pharmacy claims; ICB summaries", "question": "Where do claim stages warrant an operational evidence question?", "url": "https://www.nhsbsa.nhs.uk/prescription-data/dispensing-data/nhs-discharge-medicines-service", "licence": { "name": "File-specific reuse terms to verify", "url": "https://www.nhsbsa.nhs.uk/prescription-data/dispensing-data/nhs-discharge-medicines-service", "status": "verify_before_ingestion" }, "latestObservedPeriod": "July 2026 listed", "currentResourceUrl": null, "retrieval": null, "notes": [ "No claim files ingested. Claim submission month is not necessarily referral month or completion month.", "Counts are not referral-denominator conversion rates or clinical outcomes." ], "citation": "NHS Business Services Authority (n.d.) Discharge Medicines Service claims. Available at: https://www.nhsbsa.nhs.uk/prescription-data/dispensing-data/nhs-discharge-medicines-service (Accessed: 13 October 2026)." }, { "id": "nms", "title": "New Medicine Service claims", "publisher": "NHS Business Services Authority", "area": "medicines", "sourceCadence": "Monthly", "integrationStatus": "catalogued", "scope": "Claimed service activity and ICB or contractor reporting", "question": "How does recorded service activity compare with an organisation\u2019s defined eligible opportunity?", "url": "https://www.nhsbsa.nhs.uk/prescription-data/dispensing-data/complete-new-medicine-service-data", "licence": { "name": "File-specific reuse terms to verify", "url": "https://www.nhsbsa.nhs.uk/prescription-data/dispensing-data/complete-new-medicine-service-data", "status": "verify_before_ingestion" }, "latestObservedPeriod": "July 2026 listed", "currentResourceUrl": null, "retrieval": null, "notes": [ "No claim files ingested. The publisher describes an April 2025 change to intervention and follow-up consultation reporting.", "A claim is not evidence of adherence improvement, a complete clinical pathway or unfilled customer demand." ], "citation": "NHS Business Services Authority (n.d.) New Medicine Service claims. Available at: https://www.nhsbsa.nhs.uk/prescription-data/dispensing-data/complete-new-medicine-service-data (Accessed: 13 October 2026)." }, { "id": "drug-tariff", "title": "Drug Tariff", "publisher": "NHS Business Services Authority", "area": "medicines", "sourceCadence": "Monthly, with published updates", "integrationStatus": "catalogued", "scope": "England and Wales reimbursement rules, listed products and prices", "question": "Which reimbursement definition applies in the month under review?", "url": "https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/drug-tariff", "licence": { "name": "Publication-specific reuse terms to verify", "url": "https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/drug-tariff", "status": "verify_before_ingestion" }, "latestObservedPeriod": "October 2026 Part IX listed", "currentResourceUrl": null, "retrieval": null, "notes": [ "Tariff files not ingested or converted into a pricing service.", "Tariff reimbursement is not a pharmacy\u2019s acquisition price, realised margin or a universal medicines price." ], "citation": "NHS Business Services Authority (n.d.) Drug Tariff. Available at: https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/drug-tariff (Accessed: 13 October 2026)." }, { "id": "desnz-factors", "title": "Greenhouse-gas conversion factors 2026", "publisher": "Department for Energy Security and Net Zero", "area": "resources", "sourceCadence": "Annual, with revision notices", "integrationStatus": "dataset_retrieved", "scope": "UK activity-based greenhouse-gas reporting factors for 2026", "question": "Which dated factor and accounting boundary fit a measured resource activity?", "url": "https://www.gov.uk/government/publications/greenhouse-gas-reporting-conversion-factors-2026", "licence": { "name": "Open Government Licence v3.0", "url": "https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/", "status": "verified" }, "latestObservedPeriod": "2026 factors; revised flat file 31 July 2026", "currentResourceUrl": "https://assets.publishing.service.gov.uk/media/6a6c9748862aaf18d9c62ac9/ghg-conversion-factors-2026-flat-format-revised.xlsx", "retrieval": { "url": "https://assets.publishing.service.gov.uk/media/6a6c9748862aaf18d9c62ac9/ghg-conversion-factors-2026-flat-format-revised.xlsx", "retrievedAt": "2026-10-13T23:03:50.793785+00:00", "sha256": "a9a455ab396dae226d510c7be6233748416d490c41a5d20f3dc7a0c45feecd5e", "bytes": 515426, "verifiedAt": null, "timeBasis": "Recorded download completion" }, "notes": [ "Revised 515,426-byte flat workbook retrieved. Selected factor reference rows extracted; no company emissions inventory or savings result computed.", "July correction distinguishes unavailable values from erroneous zeros. Missing factors must stay missing.", "PMI, energy demand and greenhouse-gas emissions measure different things. A material ratio is not a carbon calculation." ], "citation": "Department for Energy Security and Net Zero (2026) Greenhouse-gas conversion factors 2026. Available at: https://www.gov.uk/government/publications/greenhouse-gas-reporting-conversion-factors-2026 (Accessed: 14 October 2026)." }, { "id": "acs-pmi", "title": "Process Mass Intensity method", "publisher": "American Chemical Society | Green Chemistry Institute", "area": "resources", "sourceCadence": "Method reference; inspect dated guidance", "integrationStatus": "method_reference", "scope": "Material input mass per mass of isolated product within a consistent process boundary", "question": "Which material inputs dominate a process, including water?", "url": "https://www.acs.org/green-chemistry-sustainability/green-chemistry-nexus/articles/process-mass-intensity-calculation-tool.html", "licence": { "name": "ACS published method; source citation, not a reusable industrial dataset", "url": "https://www.acs.org/green-chemistry-sustainability/green-chemistry-nexus/articles/process-mass-intensity-calculation-tool.html", "status": "method_citation" }, "latestObservedPeriod": "Method article published 16 October 2014", "currentResourceUrl": null, "retrieval": null, "notes": [ "NEUVIOR implements the published arithmetic in its educational resource explorer. Worked-example inputs are explicitly invented.", "No ACS industrial benchmark dataset, certification, source software redistribution or NEUVIOR process-performance result is claimed." ], "citation": "American Chemical Society | Green Chemistry Institute (2014) Process Mass Intensity method. Available at: https://www.acs.org/green-chemistry-sustainability/green-chemistry-nexus/articles/process-mass-intensity-calculation-tool.html (Accessed: 14 October 2026)." }, { "id": "ema-chemistry", "title": "Chemistry of active substances guideline", "publisher": "European Medicines Agency", "area": "resources", "sourceCadence": "On guideline revision", "integrationStatus": "document_retrieved", "scope": "EMA/CHMP/QWP/49484/2026; adopted 16 February, effective 1 September 2026", "question": "What process, recovered-material and impurity controls belong in a resource proposal?", "url": "https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-chemistry-active-substances_en.pdf", "licence": { "name": "Reproduction authorised with source acknowledgement", "url": "https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-chemistry-active-substances_en.pdf", "status": "verified_document_notice" }, "latestObservedPeriod": "2026 guideline; effective 1 September 2026", "currentResourceUrl": "https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-chemistry-active-substances_en.pdf", "retrieval": { "url": "https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-chemistry-active-substances_en.pdf", "retrievedAt": "2026-10-13T23:03:51.312369+00:00", "sha256": "a980209d02ee120c09a0c32f7362f1101739067cc0a1c954d498625a5eab85b4", "bytes": 362672, "verifiedAt": null, "timeBasis": "Recorded download completion" }, "notes": [ "Current guideline PDF retrieved and version identified. This is regulatory context, not an industrial measurement dataset.", "A recovered input still needs product-specific process and quality evaluation. Source citation does not establish programme regulatory approval." ], "citation": "European Medicines Agency (2026) Chemistry of active substances guideline. Available at: https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-chemistry-active-substances_en.pdf (Accessed: 14 October 2026)." }, { "id": "open-targets", "title": "Open Targets Platform", "publisher": "Open Targets", "area": "research", "sourceCadence": "Quarterly platform releases", "integrationStatus": "catalogued", "scope": "Integrated target\u2013disease evidence and annotations", "question": "Which published associations support a research hypothesis, and through what evidence?", "url": "https://platform.opentargets.org/", "licence": { "name": "CC0 1.0; inspect source provenance and terms", "url": "https://platform-docs.opentargets.org/licence", "status": "verified_platform_licence" }, "latestObservedPeriod": "Platform 26.9 shown; no data acquired", "currentResourceUrl": null, "retrieval": null, "notes": [ "No target rankings or GLIO association analysis downloaded in this foundation.", "Association scores integrate heterogeneous evidence and are not treatment effectiveness, causal proof or proprietary NEUVIOR findings." ], "citation": "Open Targets (n.d.) Open Targets Platform. Available at: https://platform.opentargets.org/ (Accessed: 13 October 2026)." }, { "id": "clinicaltrials", "title": "ClinicalTrials.gov public study records", "publisher": "US National Library of Medicine", "area": "research", "sourceCadence": "Source records updated by responsible parties; API refresh is source-controlled", "integrationStatus": "analysed", "scope": "Bounded glioblastoma condition-search metadata, explicit-label subset and record-type views", "question": "Which GLIO study designs and eligibility patterns merit scientific review?", "url": "https://clinicaltrials.gov/data-api/about-api", "licence": { "name": "NLM attribution and dated-snapshot terms; third-party rights may apply", "url": "https://www.nlm.nih.gov/databases/download.html", "status": "verified_attribution_and_freshness" }, "latestObservedPeriod": "14 October 2026 snapshot; all registry years", "currentResourceUrl": "https://clinicaltrials.gov/api/v2/studies?query.cond=glioblastoma&fields=NCTId%2CBriefTitle%2COverallStatus%2CStudyType%2CPhase%2CHasResults%2CCondition%2CLastUpdatePostDate%2CStudyFirstPostDate&pageSize=1000&countTotal=true&format=json", "retrieval": { "url": "https://clinicaltrials.gov/api/v2/studies?query.cond=glioblastoma&fields=NCTId%2CBriefTitle%2COverallStatus%2CStudyType%2CPhase%2CHasResults%2CCondition%2CLastUpdatePostDate%2CStudyFirstPostDate&pageSize=1000&countTotal=true&format=json", "retrievedAt": "2026-10-13T23:21:05+00:00", "sha256": "2d5286bdffd1bff59b0984b71abab5c871734c19aef159d7344ebbd74d79f9d7", "bytes": 2066351, "verifiedAt": null, "timeBasis": "Saved decoded API response completion; three pages acquired together" }, "notes": [ "A complete bounded condition search returned 2,273 unique public records across three pages; 1,773 contain an explicit glioblastoma condition label. The API reported its source data timestamp as 13 October 2026, separately from our 14 October retrieval.", "Search matches can include broader cancer or CNS studies. Completion and registry results posting are separate facts.", "No participants, contacts, interventions, outcomes or private NEUVIOR hypotheses were requested or analysed.", "Dated snapshot may not reflect current or accurate registry data. NLM is acknowledged as the source and does not endorse NEUVIOR." ], "citation": "US National Library of Medicine (n.d.) ClinicalTrials.gov public study records. Available at: https://clinicaltrials.gov/data-api/about-api (Accessed: 14 October 2026)." } ] }